Located between the amphitheatre shape Morainic hills of Lake Garda, Muscoline is a town in the province of Brescia with ancient origins: some findings traced in the area attest the presence of man since prehistoric times. Regarding the origin of the town's name there is an unanimous agreement. According to some, infact, it derives from the diminutive of "muscus" (musk), while according to others, the name comes from the cultivation of muscat grapes, grown in the area. This last proposal is confirmed by the names, assigned to some of the other villages of the area, such as Longovina (long vine).
A Ligurian settlement between the IV and V centuries B.C., followed by the Etruscans, the Gauls Cenomani. Evidence of these populations is in the names of some nearby towns such as Burago and Terzago and the presence of antique altars, entitled to the god Mercury, worship continued by the Romans who reduced to obedience the Cenomani in 197.
In the district of Castello, there are ruins of a medieval castle, dating from the IX or X century, built to defend the village from the barbarian invasions.
The Church of Saints Quirico and Giuditta was built in the XV century by the Carmelites. Inside there are frescoes of the XV and XVI centuries, including one signed by Giovanni da Ulma.
Between the XV and XVI century were built, the Churches of:

- the Church of San Giovanni Battista di Cabianca which hosts the "Baptism of Christ", an important masterpiece of the artist Pietro Marone of Brescia;

- the Church of San Pietro di Morsone, where it is possible to admire an interesting painting "the delivery of the keys" by Antonio Gandino;

- the Church of Our Lady of Burago with a Gandinian altarpiece that features "the Madonna and Child with SS. Joseph and Francis;

- the Church of San Rocco of Moniga in the woods.
In 1720 the Parish Church entitled to Santa Maria Assunta was rebuilt: an imposing building, with a nave, which recalls the one of Gavardo. The building was later enlarged and refurbished in the early XIX century and again in the XX century. Inside it preserves altarpieces of considerable artistic interest, such as the XVII century "Assumption of Our Lady" of the Milanese painter Giuseppe Nuvolone and another artwork of the XVI century completed by the Morettesca school.